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Who We Are

MAGIC stands for Metabolics and Genetics in Canada. We are a medical clinic that specializes in looking after patients (children and adults) with rare diseases that are due to changes in their DNA. Things like Lysosomal Storage Diseases (Fabry disease, Gaucher disease, Pompe disease to name a few), Mitochondrial Diseases, and overall more than 2,000 known different genetic diseases.

What We Do

We offer 2 basic services: diagnosis and treatment. We use standard methods of diagnosis through the health care system that are available at no extra cost to the patient. We also have developed our own genomic platforms – you can decide which one is the choice you would like to make. We will still aim to look after you in the best possible way to achieve the best health care outcome for your rare disease. We are always trying to find ways to give you the highest value in diagnostic testing and treatment. We will work with insurance companies and public resources to help you understand what services are available.


If you choose to do so, you can select products like whole genome or exome sequencing (WGS or WES), mitochondrial DNA (mtDNA) Nanopore genome sequencing, pharmacogenomic profiling, non-invasive prenatal (NPS) or testing of individual genes. We can send you test kits and interact with you without you having to come into the clinic because of the COVID19 pandemic situation. This allows you to get faster answers on whether or not there is an underlying genetic disease, rather than waiting for a physical appointment.


Dr. Khan has extensive experience in diagnosing and treating mitochondrial diseases and published the largest clinical trial in Canada, called MITO-FIND, focusing on using DNA sequencing methods to diagnose mitochondrial disease.  After having performed hundreds of muscle biopsies on children and adults, he worked with his team to develop a mitochondrial DNA sequencing method that can make a diagnosis from a cheek swab using Nanopore sequencing without the need to do a muscle biopsy in the majority of cases.

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